Use este identificador para citar ou linkar para este item:
http://repo.saocamilo-sp.br:8080/jspui/handle/123456789/1984
Registro completo de metadados
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Penna, Gustavo Tempone Cardoso | en_US |
dc.contributor.author | Lelot, Gabriela de Rezende | en_US |
dc.contributor.author | Lelot, Ana Luiza de Rezende | en_US |
dc.contributor.author | Hernandez, Juliana Greghi | en_US |
dc.contributor.author | Figueiredo, Carolina Costa | en_US |
dc.contributor.author | Evangelista, Nara Michelle de Araujo | en_US |
dc.contributor.author | Fernandes, Vania de Fatima Tonetto | en_US |
dc.contributor.author | Colares Neto, Guido de Paula | en_US |
dc.date.accessioned | 2024-09-09T14:16:52Z | - |
dc.date.available | 2024-09-09T14:16:52Z | - |
dc.date.issued | 2023 | - |
dc.identifier.citation | Penna, Gustavo Tempone Cardoso, et al. “Effect of recombinant human growth hormone treatment in a patient with short stature associated with the ring chromosome 17 syndrome”. Case Reports in Pediatrics, organizado por Vjekoslav Krzelj, vol. 2023, setembro de 2023, p. 1–4. DOI.org (Crossref), https://doi.org/10.1155/2023/6686511. | en_US |
dc.identifier.issn | 2090-6811 | - |
dc.identifier.uri | http://repo.saocamilo-sp.br:8080/jspui/handle/123456789/1984 | - |
dc.description.abstract | Background. Ring chromosome 17 syndrome is a rare hereditary disorder whose prevalence is less than 1 :1.000.000. We present a ten-year-old patient with ring chromosome 17 syndrome who had short stature and was treated with recombinant human growth hormone (rhGH). Case Report. A ten-year-old male scholar had moderate left conductive deafness, left kidney hypoplasia with hypertension, epilepsy, malformations in hands, feet, and abdomen, and disproportionately short stature. Despite no evidence of growth hormone defciency, rhGH treatment was indicated as a therapeutic test due to his decelerated growth velocity and severe short stature. As a result, his growth velocity increased by 4.2 cm per year and his stature Z-score increased (from −5.87 to −5.23). Conclusion. Te patient’s severe short stature may be related to genetic, environmental, and hormonal factors and the positive response to rhGH may indicate abnormalities in the somatotropic axis that were mitigated with the treatment. Although rhGH associated with adequate comorbidities controls improved his growth velocity and height Z-score, its efects in the long term are still unclear. | - |
dc.description.abstract | Background. Ring chromosome 17 syndrome is a rare hereditary disorder whose prevalence is less than 1 :1.000.000. We present a ten-year-old patient with ring chromosome 17 syndrome who had short stature and was treated with recombinant human growth hormone (rhGH). Case Report. A ten-year-old male scholar had moderate left conductive deafness, left kidney hypoplasia with hypertension, epilepsy, malformations in hands, feet, and abdomen, and disproportionately short stature. Despite no evidence of growth hormone defciency, rhGH treatment was indicated as a therapeutic test due to his decelerated growth velocity and severe short stature. As a result, his growth velocity increased by 4.2 cm per year and his stature Z-score increased (from −5.87 to −5.23). Conclusion. Te patient’s severe short stature may be related to genetic, environmental, and hormonal factors and the positive response to rhGH may indicate abnormalities in the somatotropic axis that were mitigated with the treatment. Although rhGH associated with adequate comorbidities controls improved his growth velocity and height Z-score, its efects in the long term are still unclear. | - |
dc.publisher | Wiley Online Library | en_US |
dc.relation.ispartof | Case reports in pediatrics, v. 2023, 2023, p. 1–4 | en_US |
dc.subject | Hormônio do crescimento humano | en_US |
dc.subject | Cromossomos humanos Par 17 | en_US |
dc.title | Effect of recombinant human growth hormone treatment in a patient with short stature associated with the ring chromosome 17 syndrome | en_US |
dc.type | Artigo de Periódico | en_US |
dc.identifier.doi | 10.1155/2023/6686511 | - |
Aparece nas coleções: | Artigos de Periódicos |
Arquivos associados a este item:
Não existem arquivos associados a este item.
Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.