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Campo DC | Valor | Idioma |
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dc.contributor.author | Campos, Raquel Munhoz da Silveira | en_US |
dc.contributor.author | Masquio, Deborah Cristina Landi | en_US |
dc.contributor.author | Corgosinho, Flávia Campos | en_US |
dc.contributor.author | Carvalho-Ferreria, Joana Pereira de | en_US |
dc.contributor.author | Netto, Bárbara Dal Molin | en_US |
dc.contributor.author | Clemente, Ana Paula Grotti | en_US |
dc.contributor.author | Tock, Lian | en_US |
dc.contributor.author | Tufik, Sergio | en_US |
dc.contributor.author | Mello, Marco Túlio de | en_US |
dc.contributor.author | Dâmaso, Ana Raimunda | en_US |
dc.date.accessioned | 2023-09-11T19:33:04Z | - |
dc.date.available | 2023-09-11T19:33:04Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | CAMPOS, R. M. D. S. et al. Relationship between adiponectin and leptin on osteocalcin in obese adolescents during weight loss therapy. Archives of Endocrinology and Metabolism, 7 maio 2018. | en_US |
dc.identifier.uri | http://repo.saocamilo-sp.br:8080/jspui/handle/123456789/1500 | - |
dc.description.abstract | Objectives: Obesity is a multifactorial disease characterized by the presence of the pro-inflammatory state associated with the development of many comorbidities, including bone turnover marker alterations. This study aimed to investigate the role of the inflammatory state on bone turnover markers in obese adolescents undergoing interdisciplinary weight loss treatment for one year. Subjects and methods: Thirty four post-pubescent obese adolescents with primary obesity, a body mass index (BMI) greater than > 95th percentile of the CDC reference growth charts, participated in the present investigation. Measurements of body composition, bone turnover markers, inflammatory biomarkers and visceral and subcutaneous fat were taken. Adolescents were submitted to one year of interdisciplinary treatment (clinical approach, physical exercise, physiotherapy intervention, nutritional and psychological counseling). Results: Reduction in body mass, body fat mass, visceral and subcutaneous fat, as well as, an increase in the body lean mass and bone mineral content was observed. An improvement in inflammatory markers was seen with an increase in adiponectin, adiponectin/leptin ratio and inteleukin-15. Moreover, a positive correlation between the adiponectin/ leptin ratio and osteocalcin was demonstrated. Further, both lean and body fat mass were predictors of osteocalcin. Negative associations between leptin with osteocalcin, adiponectin with Beta CTX collagen, and visceral fat with adiponectin were observed. Conclusions: It is possible to conclude that the inflammatory state can negatively influence the bone turnover markers in obese adolescents. In addition, the interdisciplinary weight loss treatment improved the inflammatory state and body composition in obese adolescents. Therefore, the present findings should be considered in clinical practice | en_US |
dc.publisher | Official Journal of the Brazilian Society of Endocrinology and Metabolism | en_US |
dc.relation.ispartof | Archives of endocrinology and metabolism | en_US |
dc.subject | Inflamação | en_US |
dc.subject | Obesidade | en_US |
dc.subject | Adolescente | en_US |
dc.subject | Redução de peso | en_US |
dc.subject | Marcadores de renovação óssea | en_US |
dc.title | Relationship between adiponectin and leptin on osteocalcin in obese adolescents during weight loss therapy, 2018;62(3):275-84 | en_US |
dc.type | Artigo de Periódico | en_US |
dc.identifier.doi | 10.20945/2359-3997000000039 | - |
Aparece nas coleções: | Artigos de Periódicos |
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